Benzothiopyranyl derivatives as HMG-CoA reductase inhibitors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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549 23, A61K 3138, C07D33506

Patent

active

049468600

ABSTRACT:
Disclosed are novel benzothiopyranyl derivatives as 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors useful as antihypercholesterolemic agents represented by the formula: ##STR1## their corresponding dihydroxy acids, and pharmaceutically acceptable salts thereof.

REFERENCES:
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patent: 4611067 (1986-09-01), Volante et al.
patent: 4668699 (1987-05-01), Hoffman et al.
patent: 4897402 (1990-01-01), Duggan et al.

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