Benzothiopyranyl derivatives as HMG-CoA reductase inhibitors

Details Benzothiopyranyl derivatives as HMG-CoA reductase inhibitors Benzothiopyranyl derivatives as HMG-CoA reductase inhibitors

1989-11-03

1990-08-07

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

549 23, A61K 3138, C07D33506

Patent

active

049468600

ABSTRACT:
Disclosed are novel benzothiopyranyl derivatives as 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors useful as antihypercholesterolemic agents represented by the formula: ##STR1## their corresponding dihydroxy acids, and pharmaceutically acceptable salts thereof.

REFERENCES:
patent: 4282155 (1981-08-01), Smith et al.
patent: 4611067 (1986-09-01), Volante et al.
patent: 4668699 (1987-05-01), Hoffman et al.
patent: 4897402 (1990-01-01), Duggan et al.

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