Drug – bio-affecting and body treating compositions – Addiction
Patent
1988-08-17
1990-09-11
Friedman, Stanley H.
Drug, bio-affecting and body treating compositions
Addiction
424 10, A61K 2700
Patent
active
049563912
ABSTRACT:
The invention presented is a composition for the treatment of individuals addicted to narcotics or individuals having age-related condition such as tinnitus and Alzheimer's comprising a protected complex of procaine and a complexing agent for procaine in an amount effective to reduce the withdrawal symptoms of individuals addicted to narcotics or the symptoms of tinnitus and Alzheimer's disease.
REFERENCES:
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patent: 2684323 (1954-07-01), Ruskin
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Johanson, et al., "Comparison of the Reinforcing Properties of Cocaine and Procaine in Rhesus Monkeys", Pharm. Bio. & Beh., vol. 15, pp. 49-53, 1981.
Johanson, "The Reinforcing Properties of Procaine, Chloroprocaine and Proparacaine in Rhesus Monkeys", Psychopharmacology 67, 189-194, 1980.
Gold, et al., "Clonidine Blocks Acute, Opiate-Withdrawal Symptoms", The Lancet, 1978, 599-601.
Charney, et al., "Clonidine and Naltrexone, A Safe, Effective, and Rapid Treatment of Abrupt Withdrawal From Methadone Therapy", Arch Gen Psychiatry, vol. 39, 11/82.
Kleber, et al., "Clonidine in Outpatient Detoxification From Methadone Maintenance", Arch Gen Psychiatry, vol. 42, 4/85.
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