YH206 cell line and monoclonal antibody produced by it

Details YH206 cell line and monoclonal antibody produced by it YH206 cell line and monoclonal antibody produced by it

1990-01-12

1991-02-05

Moskowitz, Margaret

Chemistry: molecular biology and microbiology

Spore forming or isolating process

530387, 530808, 530809, 424 858, C12N 500, A61K 3514, C07K 300, C07K 1500

Patent

active

049904540

ABSTRACT:
A monoclonal antibody specifically reactive to a human adenocarcinoma cell, which is obtainable by cultivating a fused cell obtained by fusing a mammalian animal cell, immunized with a human adenocarcinoma cell, with a myeloma cell.

REFERENCES:
patent: 4683200 (1987-07-01), Hirohashi et al.
Endo, T. et al., "Preparation of a Monoclonal Antibody to Human Lung Adenocarcinoma Cells and Detection of Corresponding Antigen(s) in Sera of Malignant Diseases", Sapporo Med. J., vol. 54, No. 4, pp. 393-410, Oct., 1985.
Iguro, T. et al., "Sialylated Lewis* Antigen Detected in the Sera of Cancer Patients", The Lancet, vol. II, pp. 817-818, Oct. 6, 1984.
Vark, N. M. et al., "Antigens Associated with a Human Lung Adenocarcinoma Defined by Monoclonal Antibodies", Cancer Research, vol. 44, pp. 681-687, Feb., 1984.
Zimmer, A. M. et al., (I) "Radioimmunoscintigraphy of Human Lung Adenocarcinoma with Iodine-131 Tumor-Specific Monoclonal Antibody", 4th Annual Congress for Hybridoma Research, San Francisco, Calif., U.S.A., Feb. 3-6, 1985, Hybridoma, vol. 4, No. 1, p. 72, 1985.
Zimmer, A. M. et al. (II), "Radioimmunoscintigraphy of Human Lung Adenocarcinoma with .sup.131 I Tumor-Specific Monoclonal Antibody", 30th Annual Meeting of the Society of Nuclear Medicine (Central Chapter), Chicago, Ill., U.S.A., Mar. 21-23, 1985. J. Nucl. Med., vol. 26, No. 6, p. 675, 1985.
Lee, I., et al., "Immunohistochemical Staining of Various Lung Carcinoma Types with Monoclonal Antibody 443A-6", 42nd Annual National Meeting of the American Federation for Clinical Research, Washington, D.C., May 3-6, 1985.
Clin. Res., vol. 33, No. 2, Part 1, p. 454A, 1985.
Radosevich, J. A., "Monoclonal Antibody 44-3A6 as a Probe for a Novel Antigen Found on Human Lung Carcinomas with Glandular Differentiation", Cancer Research, vol. 45, pp. 5808-5812, Nov., 1985.
Endo, T. et al., Report of General Meeting of Japan Immunological Association, vol. 14, 123 (P. 572), "Preparation of Monoclonal Antibody to Human Lung Adenocarcinoma Cells", (Nov. 10, 1984).

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