X-ray ablation of hyaluronan hydrogels

X-ray or gamma ray systems or devices – Specific application – Lithography

Reexamination Certificate

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C378S035000

Reexamination Certificate

active

07903780

ABSTRACT:
Disclosed is a method for ablating hyaluronan-based hydrogels with X-rays, the method comprising the steps of: (a) preparing hyaluronan-based hydrogels; and (b) performing X-ray irradiation to the hyaluronan-based hydrogels to induce a degradation of the hyaluronan-based hydrogels by a gel-to-sol transition during the X-ray irradiation. Disclosed is also a method for fabricating three-dimensional microchannels of hyaluronan hydrogels with a finely tunable X-ray ablation technique.

REFERENCES:
patent: 2007/0036745 (2007-02-01), Leshchiner et al.

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