Tick galectin

Details Tick galectin Tick galectin

2006-09-22

2009-06-16

Epps-Ford, Janet (Department: 1633)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C536S023100, C424S093100

Reexamination Certificate

active

07547682

ABSTRACT:
A novel galectin, a polynucleotide encoding the same, a vector and a transformant comprising the polynucleotide, an antibody against the galectin, and a screening method for screening a substance capable of modifying the galectin, are disclosed. According to the galectin, polynucleotide, or vector, it is possible, for example, to exterminate ticks, or to treat or prevent tick-borne infections such as rickettsiosis, filariasis, Q fever, African recurrent fever, or viral encephalitis.

REFERENCES:
patent: 7135552 (2006-11-01), Fujisaki et al.
patent: WO 03/072609 (2003-09-01), None
Keller et al (Journal of Biological Chemistry. 1993; 268(8):5450-5456).
Kovar et al. Insect Biochemistry and Molecular Biology. 2000; 30:195-205.
Rego et al. (Insect Biochemistry and Molecular Biology. Apr. 2006; 36(4): 291-299).
Yagi et al,Glycoconjugate Journal, 18:745-749 (2001).
Astigarraga et al,Veterinary Parasitology, 60:133-147 (1995).
Hill et al, EMBL-EBI, Database Accession No. BF007251, XP-002328634 (Oct. 14, 2000).
Hill et al,Microbial&Comparative Genomics, 5:89-101 (2000).
Kovar et al,Biochem. Mol. Biol., 30(3):195-205 (2000).
Grubhoffer et al,Zool. Sci., 8(6):1001-1003 (1991).

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