Process for preparing amino acid esters

Details Process for preparing amino acid esters Process for preparing amino acid esters

1983-09-01

1985-01-29

Helfin, Bernard

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

560125, 560155, C07C10102

Patent

active

044967560

ABSTRACT:
A enolizable organic compound, such as benzyl chloride, is reacted with an acid amide, an alcohol, carbon monoxide, and hydrogen in a homogeneous reaction mixture containing a cobalt carbonylation catalyst, an alkali metal alcoholate, and methyl isobutyl ketone so as to form an N-acylamino acid ester such as N-acetyl-D,L-phenylalanine methyl ester.

REFERENCES:
patent: 3766266 (1973-10-01), Wakamatsu et al.
patent: 3996288 (1976-12-01), Yukata et al.
patent: 4262092 (1981-04-01), Bauer
patent: 4264515 (1981-04-01), Stern et al.

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