Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Plant proteins – e.g. – derived from legumes – algae or...
Patent
1989-05-31
1991-08-27
Moskowitz, Margaret
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Plant proteins, e.g., derived from legumes, algae or...
530350, 530419, 530412, 530421, 530362, 530363, 530364, 530418, C07K 324, C07K 326
Patent
active
050434276
ABSTRACT:
This invention relates to a process for continuously fractionating plant, animal or human proteins by selective precipitation of the proteins resulting from placing a solution of proteins in contact with a precipitating agent constituted by a fatty acid of 6 to 14 carbon atoms, such as caprylic acid, is characterized in that respective deliveries of fatty acid and of the protein solution are continuously placed in contact in a mixing chamber of small volume with respect to the deliveries, creating a strong stirring in this mixing chamber; the individual deliveries of fatty acid and of protein solution are adjusted to controlled pH and temperature so as to maintain their ratio equal to a predetermined value; the mixture is then allowed to evolve during a phase of maturation so as to form a suspension; this suspension is separated into a liquid part from which are extracted the proteins having remained soluble, and a solid part containing proteins of different nature; and the parameters intervening in the process, such as delivery, pressure, temperature, pH, resistivity, are permanently monitored. The invention also relates to an installation for carrying out said process.
REFERENCES:
patent: Re31268 (1983-06-01), Hansen
patent: 2765299 (1956-10-01), Porsche et al.
patent: 3992367 (1976-11-01), Plan et al.
patent: 4177188 (1979-12-01), Hansen
patent: 4217418 (1980-08-01), McAleer
patent: 4335214 (1982-06-01), Adamowicz
patent: 4421682 (1983-12-01), Edwards et al.
patent: 4446066 (1984-05-01), Luijerink
Preparative Biochemistry, vol. 14, No. 1, pp. 1-17, Marcel Dekker, Inc.; A.F.S.A. Habeeb et al.: "Preparation of Human Immunoglobin by Caprylic Acid Precipitation".
Method Plasma Protein Fractionation, editor J. M. Curling, pp. 33-56, Academic Press, London, U.K.; M. Steinbuch: "Proteion Fractionation by Ammonium Sulphate, Rivanol and Caprylic Acid Precipitation".
Beaudoin Gilles
Colinart Pierre
Faure Alain
Leberre Catherine
Renon Henri
Foundation Nationale de Transfusion Sanguine
Furman Keith C.
Moskowitz Margaret
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