Microorganism employed for producing streptovaricin

Details Microorganism employed for producing streptovaricin Microorganism employed for producing streptovaricin

1991-09-26

1993-01-05

Lilling, Herbert J.

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

435 34, 435119, 435180, 4352401, 435245, 4352536, 435886, C12R 1465, C12N 136, C12Q 104, C12P 1718

Patent

active

051770180

ABSTRACT:
A method for selecting hyper-producing strains of streptovaricin C by culturing streptomyces spectabilis and separating the asporogenous colonies. The asporogenous colonies are then separately cultured and tested for streptovaricin productivity. Those colonies having the highest productivity may then be easily selected.

REFERENCES:
patent: 3116202 (1963-12-01), Dietz et al.
K. L. Rinehart Jr., et al, "Relative biological activities of individual streptovaricins and streptovaricin acetates," Biochemistry vol. 13 No. 5 pp. 861-867 (1974).
K. Sasaki, et al, "Chemical modification of streptovaricins C, "J. Antibiotics vol. 29 No. 2 pp. 147-154 (Feb. 1976).
S. Ito, et al, "Selective killing of human T cell lymphotropic virus type I-transformed cell lines by a damavaricin F.sub.c derivative," J. Antibiotics vol. 42 No. 5 pp. 779-787 (May 1989).

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