Methods for inhibiting the chemotaxis of neutrophils

Details Methods for inhibiting the chemotaxis of neutrophils Methods for inhibiting the chemotaxis of neutrophils

1995-05-25

1997-09-16

Kight, John

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514 53, 514 61, 514885, 536 291, 5361231, 53612313, A61K 31715

Patent

active

056681151

ABSTRACT:
An anti-inflammatory drug comprising as the effective component at least one compound selected from the group consisting of colominic acid, partial hydrolysis products of colominic acid and pharmaceutically acceptable salts thereof. The drug is used as a drug for renal diseases, a drug for hepatitis, an immunomodulator and a drug for inhibiting the chemotaxis of neutrophil.

REFERENCES:
patent: 4740589 (1988-04-01), Moreno
Devi et al., Proc. Natl. Acad. Sci, USA, vol. 88:7175-7179, (1991).
Chang et al., Immunology, vol. 73(1):95-101, (1991) abstract only.
Corral et al., Biochem. Biophys. Res. Commun., vol. 172(3):1349-1356, (1990) abstract only.
Perez et al., J. Immunol., vol. 139(6):1978-1984, (1987) abstract only.
Ozkan et al., J. Burn Care Rehabil., vol. 7(5):388-397, (1986) abstract only.

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