Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor
Reexamination Certificate
2005-03-01
2005-03-01
Prouty, Rebecca E. (Department: 1652)
Chemistry: molecular biology and microbiology
Micro-organism, per se ; compositions thereof; proces of...
Bacteria or actinomycetales; media therefor
C435S115000, C435S252330, C435S183000, C435S194000, C435S232000, C536S023200, C536S023100, C536S024100
Reexamination Certificate
active
06861246
ABSTRACT:
The invention relates to L-lysine-producing strains of corynebacteria with enhanced pyc gene (pyruvate carboxylase gene), in which strains additional genes, chosen from the group consisting of the dapA gene (dihydrodipicolinate synthase gene), the lysC gene (aspartate kinase gene), the lysE gene (lysine export carrier gene) and the dapB gene (dihydrodipicolinate reductase gene), but especially the dapA gene, are enhanced and, in particular, over-expressed, and to a process for the preparation of L-lysine.
REFERENCES:
patent: 6200785 (2001-03-01), Kreutzer et al.
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patent: 0 435 132 (1991-07-01), None
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patent: 0 108 790 (2001-06-01), None
patent: WO 01 00 844 (2001-01-01), None
Database EMBL “Online” Accession No. X67737, Apr. 1, 1993, “C. glutamicum dapb gene for dihydrodipicolinate reductase” XP002151598.
Partial English language translation of DE 198 31 609 A.
Partial English language translation of DE 195 48 222A.
Partial English language translation of EP 0435 132 A.
Eggeling Lothar
Kreutzer Caroline
Mockel Bettina
Patek Miroslav
Pfefferle Walter
Degussa - AG
Pillsbury & Winthrop LLP
Prouty Rebecca E.
Ramirez Delia M.
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