Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...
Patent
1979-10-29
1981-08-11
Jiles, Henry R.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Parasitic organism or component thereof or substance...
424256, 424258, 546 15, 548301, A61K 31415
Patent
active
042834090
ABSTRACT:
A series of novel spiro-imidazolone compounds and their pharmaceutically acceptable acid addition salts are disclosed. These particular compounds are useful in therapy as agents for the control of certain chronic diabetic complications. 3',4'-Dihydro-spiro-[imidazolidine-4,1'(2'H)naphthalene]-5-one represents a typical and preferred member compound. Methods for preparing all these compounds from known hydantoin starting materials are provided.
REFERENCES:
patent: 3821383 (1974-06-01), Sestanj et al.
Granger et al. Chem. Abst. vol. 70, 1969, 24392a.
Faust et al. Jour. of the Ameri. Pharmaceutical Association vol. 46, No. 2, pp. 118-123, 1957.
Belletire John L.
Sarges Reinhard
Fan Jane T.
Jiles Henry R.
Knuth Charles J.
Murphy Francis X.
Pfizer Inc.
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