Flavour modulating substances

Food or edible material: processes – compositions – and products – Products per se – or processes of preparing or treating... – Flavor per se – or containing flavor or flavor improver of...

Reexamination Certificate

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C426S536000

Reexamination Certificate

active

08053013

ABSTRACT:
The present invention in a first aspect relates to novel flavour modulating substances according to formula (I) or formula (II) or edible salts thereof or both: R1—CR2(OR3)—CO—NR4—CHR5R6(I). It was found that substances represented by formula (I) or formula (II) can advantageously be used to impart desirable flavour, especially taste attributes to foodstuffs, beverages, pharmaceutics, tobacco products and oral care products they are incorporated in. In addition these substances are capable of modulating and complementing the sensory impact of other, flavour imparting, substances. Thus, the present flavour modulating substances are advantageously applied in flavour compositions, foodstuffs, beverages, pharmaceutics and oral care products. Typical examples of flavour modulating substances according to the present invention include N-lactoyl glucosamine, N-lactoyl glucosaminic acid, N-gluconyl glucosamine, N-gluconyl glucosaminic acid, hemiacetals or lactones thereof, edible salts thereof and mixtures thereof.

REFERENCES:
patent: 5624906 (1997-04-01), Vermeer
patent: 6287620 (2001-09-01), Van Den Ouweland et al.
patent: 6956029 (2005-10-01), Maier et al.
patent: 2003/0143661 (2003-07-01), Lorbert et al.
patent: 2004/0071855 (2004-04-01), Wassenaar
patent: 2004/0072254 (2004-04-01), Callamaras et al.
patent: 2005/0013846 (2005-01-01), Pelan et al.
patent: 2009/0169696 (2009-07-01), Renes et al.
patent: 297 167 (1992-01-01), None
patent: 1 291 342 (2003-03-01), None
patent: 1 401 500 (2004-03-01), None
patent: 2 757 180 (1998-06-01), None
patent: 1 420 909 (1974-09-01), None
patent: 2 396 414 (2004-06-01), None
patent: 90/06689 (1990-06-01), None
patent: 92/06601 (1992-04-01), None
patent: 97/04667 (1997-02-01), None
patent: 01/77292 (2001-10-01), None
patent: 02/100192 (2002-12-01), None
patent: 03/049696 (2003-06-01), None
patent: 2004/055048 (2004-07-01), None
patent: 2004/075633 (2004-09-01), None
NPL from “Chemical Book.com” showing chemical structure of Glucosamine, retrieved Oct. 7, 2009.
B. Lindemann, “Receptors and Transduction in Taste”, Nature, Sep. 13, 2001, pp. 219-225, vol. 413.
(MSG) H. Suzuki et al., “Improvement of the bitter Taste of Amino Acids Through the Transpeptidation Reaction of Backerial y-Glutamyltranspeptidase”, J. Agric. Food Chem., 2002, pp. 313-318, vol. 50, No. 2.
K. Shima et al., “Novel Brothy Taste Modifier Insolated from Beef Broth”, J. Agric Food Chem., 1998, pp. 1465-1468, vol. 46, No. 4.
Y. Ueda et al., “Flavor Characteristics of Glutathione in Raw and Cooked Foodstuffs”, Biosc. Biotech. Biochem., 1997, pp. 1977-1980, vol. 61, No. 12.
A. N. Pronin et al., “Identification of Ligands for Two Human Bitter T2R Receptors”,Chemical Senses, 2004, pp. 583-593, vol. 29.
P. A. Breslin, “Interactions Among Salty, Sour and Bitter Compounds”, Trends in Food Science and Technology, Dec. 1996, pp. 390-399, vol. 7.
M. Cliff et al., “Descriptive analysis of Oral Pungency”, J Sensory Studies, Feb. 24, 1992, pp. 279-290, vol. 7.
P. Dalton et al., The Merging of the Senses: Integration of Subthreshold Taste and Smell, Nature Neurosci., May 2000, pp. 431-432, vol. 3, No. 5.
Database Beilstein, Beilstein Crossfire Institut Zur Foerderung der Chemischen Wissenschaften; BRN 8218971, “Acetic acid (2,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-3-ylcarbamoyl)-methyl ester” Feb. 29, 2000, XP002379570, Abstract.
Database Beilstein, Beilstein Crossfire Institut Zur Foerderung der Chemischen Wissenschaften; BRN 7137987, “3- hydroxy-2-(2,3,4,5,6-pentahydroxy-hexanoylamino)-propionic acid” Jul. 28, 1995, XP002379571, Abstract.
Database Biosis [Online], Biosciences Information Service, Philadelphia, PA, US; 1989, Valcavi U. et al., “New Potential Immunoenhancing Compounds Synthesis and Pharmacological Evaluation of New Long-Chain 2 Amido-2-Deoxy-D-Glucose Derivatives”, XP002379572, Database accession No. PREV199089051988 Abstract.
Valcavi et al., “New Potential Immunoenhancing Compounds”, Arzneimittel-Forschung, 1989, pp. 1190-1195, vol. 39, No. 10, ISSN: 0004-4172.
Kuboki et al., “An Expeditious Route to N-Glycolylneuraminic Acid Based on Enzyme-Catalyzed Reaction”, Tetrahedron, Feb. 17, 1997, pp. 2387-2400, XP004105332, ISSN: 0040-4020, pp. 2392-2393; compounds 2A, 2C, 3A, 3C, vol. 53, No. 7, Elsevier Science Publishers, Amsterdam, NL.
Chenault et al., “Kinetic Resolution of Unnatural and Rarely Occurring Amino Acids: Enantioselective Hydrolysis of N-Acyl Amino Acids Catalyzed by Acylase I”, Journal of the American Chemical Society, Aug. 2, 1989, pp. 6354-6364, vol. 111, No. 16, XP000940668, ISSN: 0002-7863, p. 6357, left-hand column, paragraph 4; compounds 22-MA, American Chemical Society, Washington, DC.
Fialova et al., “Hydrolytic and Transglycosylation Reactions of N-Acyl Modified Substrates Catalysed by Beta-N-Acetylhexosaminidases”, Tetrahendron, Jan. 12, 2004, pp. 693-701, vol. 60, No. 3, XP004482884, ISSN: 0040-4020, compounds 5, 5A, 5B, 5C, Elsevier Science Publishers, Amsterdam, NL.
Database Beilstein, Beilstein Crossfire Institut Zur Foerderung der Chemischen Wissenschaften; BRN 1715054, “2-(2,4-dihydroxy-3,3-dimethyl-butyrylamino)-succinic acid”, Nov. 22, 1993, XP002379573, Abstract.
Database Beilstein, Beilstein Crossfire Institut Zur Foerderung der Chemischen Wissenschaften; BRN 1714863, “2-hydroxy-N-(2,4,5-trihydroxy-6-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-3-yl)-propionamide”, Sep. 20, 1991, XP002379574, Abstract.
Database Beilstein, Beilstein Crossfire Institut Zur Foerderung der Chemischen Wissenschaften; BRN 9556029, “3-hydroxy-2-(2-hydroxy-3-methyl-butyrylamino)-propionic acid”, Apr. 23, 2004, XP002379575, Abstract.
Chen et al., “P3 Cap Modified Phe*-Ala Series BACE Inhibitors”, Bioorganic & Medicinal Chemistry Letters, Jan. 5, 2004, vol. 14, No. 1, Jan. 5, 2004, pp. 245-250, XP002379562, ISSN: 0960-894X.
Database Medline [Online], US National Library of Medicine (NLM), Bethesda, MD, US; Sep. 1988, Horiuchi, T. et al., “Purification and Properties of N-Acyl-D-Mannosamine Dehydrogenase fromFlavobacteriumsp. 141-8”, XP002379576, Database Accession No. NLM3240988.
Horiuchi et al., “Purification and Properties of N-Acyl-D-Mannosamine Dehydrogenase fromFlavobacteriumsp. 141-8”, Abstract and Journal of Biochemistry, Sep. 1988, vol. 104, No. 3, pp. 466-471, ISSN: 0021-924X.
Schneider et al., “Verknuepfung Von Zuckern Mit Aminosaeureestern Lipophiler Alkohole Zu Grenzflaechenaktiven Zuckerderivaten”, Hoppe-Seyler's Zeitschrift Fuer Physiologische Chemie, Walter De Gruyter, Berlin, DE, 1963, vol. 330, pp. 182-188, XP001021387, ISSN: 0018-4888, pp. 184-188.

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