Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2006-02-13
2010-02-16
Berch, Mark L. (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S252020, C544S238000, C544S349000, C540S556000, C540S460000, C540S472000, C548S536000, C548S470000, C546S245000, C560S180000
Reexamination Certificate
active
07662812
ABSTRACT:
This invention relates to novel diazabicyclic aryl derivatives which are found to be cholinergic ligands at the nicotinic acetylcholine receptors and modulators of the monoamine receptors and transporters. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.
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Maviel, et al., Neuroscience, vol. 120, # 4, Sep. 15, 2003, pp. 1049-1059.
Dyhring Tino
Nielsen Elsebet Østergaard
Olsen Gunnar
Peters Dan
Timmermann Daniel B
Berch Mark L.
Birch Stewart Kolasch & Birch, LLP.
Jaisle Cecilia M
Neurosearch A/S
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