Benzoylguanidines, a process for their preparation, their use as

Details Benzoylguanidines, a process for their preparation, their use as Benzoylguanidines, a process for their preparation, their use as

1990-09-04

1992-02-25

Ivy, C. Warren

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514603, 514634, 546231, 564 85, 564237, A61K 31445, C07D21128, C07C27910

Patent

active

050913948

ABSTRACT:
Benzoylguanidines of the formula I ##STR1## where R(1) or R(2) is equal to R(6)--S(O).sub.n -- or R(7)R(8)N--O.sub.2 S--
and the other substituent R(1) or R(2) is in each case equal to H, F, Cl, Br, I, alkyl, alkoxy or phenoxy, R(6)--S(O).sub.n or R(7)R(8)N--
and R(6) is equal to alkyl, cycloalkyl, cyclopentylmethyl, cyclohexylmethyl or phenyl,
R(7) and R(8) are equal to alkyl or phenylakyl or phenyl,
and in which R(7) and R(8) may also together be a C.sub.4 -C.sub.7 chain, and in which R(7) and R(8), together with the nitrogen atom to which they are bonded, may be dihydroindole, tetrahydroquinoline or tetrahydroisoquinoline system,
and where R(3), R(4) and R(5) are equal to hydrogen or alkyl, or R(3) and R(4) are together an alkylene chain or R(4) and R(5) are together an alkylene chain,
and where n is equal to zero, 1 or 2 and their pharmaceutically tolerable salts are outstanding antiarrhythmics.

REFERENCES:
patent: 3780027 (1973-12-01), Cragoe
patent: 3953476 (1976-04-01), Cragoe, Jr. et al.
patent: 4761417 (1988-08-01), Maroko

Affiliated with

Also associated with

Rating

Benzoylguanidines, a process for their preparation, their use as does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Benzoylguanidines, a process for their preparation, their use as, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Benzoylguanidines, a process for their preparation, their use as will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1893165