Antibacterial oil-in-water emulsions

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai

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514552, 514943, A61K 740

Patent

active

056188404

ABSTRACT:
An antibacterial oil-in-water emulsion for inhibiting the growth of Helicobacter pylori is disclosed. The oil-in-water emulsion of the invention comprises droplets of an oily discontinuous phase dispersed in a continuous phase. The oily discontinuous phase contains an oil carrier and a glycerol ester selected from the group consisting of glycerol monooleate and glycerol monostearate. The emulsion can be positively charged, negatively charged or chargeless. In one embodiment, the emulsion is positively charged and further comprises a cationic halogen-containing compound having a C.sub.12 -C.sub.16 chain as a positive charge producing agent. In another embodiment, the emulsion is negatively charged and further comprises an negative charge producing agent having a C.sub.12 -C.sub.22 chain. The disclosed emulsions can be administered to individuals, for example, orally, to treat or prevent Helicobacter pylori infections.

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