8-Chlorodibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 2-(al

Details 8-Chlorodibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 2-(al 8-Chlorodibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 2-(al

1985-02-25

1985-12-17

Milestone, Norma S.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

2603307, C07D26720, A61K 3155

Patent

active

045593370

ABSTRACT:
This invention relates to 8-chlorodibenz[b,f][1,4]-oxazepine-10(11H)-carboxylic acid, 2-(alkoxy-containing acyl)hydrazides that are useful as prostaglandin antagonists and analgesic agents.

REFERENCES:
patent: 3534019 (1970-10-01), Coyne
patent: 3917649 (1975-11-01), Mueller
patent: 3989719 (1976-11-01), Mueller
patent: 3992375 (1976-11-01), Mueller
patent: 4045442 (1977-08-01), Mueller
patent: 4125532 (1978-11-01), Mueller
patent: 4170593 (1979-10-01), Mueller
J. H. Sanner, "Antagonism of Prostaglandin E.sub.2 by 1-Acetyl-2-(8-Chloro-10,11-Dihydrodibenz[b,f][1,4]Oxazepine-10-Carbonyl)Hy drazine (SC-19220)," Arch. Int. Pharmacodyn., 180, 46, (1969).

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