Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1973-08-08
1976-03-23
Weinberger, Lorraine A.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
C07D31768
Patent
active
039460410
ABSTRACT:
The present invention relates to the preparation of novel rheadan-type alkaloids and to novel intermediates useful in the preparation thereof. The process utilizes as starting materials a known class of alkaloids of the narcotine or of the hydrastine type. Certain of the said novel intermediates are also pharmaceutically useful in and of themselves. Additionally, certain of the novel intermediates can be converted into other type alkaloids which are also pharmaceutically useful.
REFERENCES:
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Kelentei et al., Arch. exptl. Pathol. Pharmakol, 233, pp. 550-555 (1958).
Addinall et al., J.A.C.S. 55, pp. 2153-2163, (1933).
Stecher, The Merck Index, 8th Ed., pp. 719-720 (1968).
Morrison et al., Organic Chemistry, 2nd Ed., (1966), pp. 601-603.
Whaley et al., J. Org. Chem. 19, (1954), pp. 666-669.
Brossi Arnold
Kloetzer Wilhelm
Teitel Sidney
Hoffmann-La Roche Inc.
Isgro William G.
Leon Bernard S.
Shippen Michael
Weinberger Lorraine A.
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