3-substituted 2-hydroxy-3-formylpropionic esters, the preparatio

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters

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560212, C07C 69675, C07C 69732

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active

052568130

ABSTRACT:
A 3-substituted 2-hydroxy-3-formylpropionic ester of the formula I ##STR1## where R.sup.1 is lower alkyl, and R.sup.2 is straight-chain or branched alkyl of 1 to 10 carbon atoms, is obtained by adding an alkanal of the fomrula II ##STR2## and an alkyl glyoxylate of the formula III ##STR3## simultaneously to a catalyst system composed of a salt or a mixture of a secondary amine and a carboxylic acid in such a way that the temperature does not exceed 90.degree. C., preferably 80.degree. C., or else adding one of the reactants of the formula II or III to a mixture of the catalyst system described above and the other reactant in such a way that the temperature does not exceed 90.degree. C. The 2-hydroxy-3-formylpropionic eater of the formula I can be converted by treatment with dehydrating agents, especially acetic anhydride, into good yields of the corresponding 3-substituted 3-formylacrylic ester.

REFERENCES:
patent: 3984440 (1976-10-01), Bollag et al.
patent: 4215215 (1980-07-01), Bollag et al.
patent: 4230872 (1980-10-01), Klaus et al.
patent: 4656310 (1987-04-01), Bollag et al.

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