2,2,3-trimethylcyclopentenyl acetone derivatives, organoleptic u

Perfume compositions – Perfume compositions – Ring containing active ingredient

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512 16, 512 18, 512 26, 512 27, 568377, A61K 746

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active

050396595

ABSTRACT:
Described are 2,2,3-trimethylcyclopentenyl acetone derivatives defined according to one or a mixture of compounds having the structures: ##STR1## organoleptic uses thereof, processes for preparing same using as a starting material the compound having the structure: ##STR2## which is reacted to form the compound having the structure: ##STR3## which is further reacted to form the novel intermediate: ##STR4## which is then converted to the 2,2,3-trimethylcyclopentenyl acetone derivatives or our invention using the allylic alcohol having the structure: ##STR5## wherein R.sub.3, R.sub.4, and R.sub.5 are the same or different hydrogen or methyl; R.sub.6 represents hydrogen, methyl, ethyl, or propyl or isopropyl; x is 0, 1 or 2; R.sub.7 is methyl or ethyl; R.sub.7 ' and R.sub.7 " represent methyl or ethyl or R.sub.7 ', (CH.sub.2).sub.x and R.sub.7 " taken together represents C.sub.2 -C.sub.6 alkylene; M represents Li, Mg, X or MgX; and X represents chloro or bromo.

REFERENCES:
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patent: 4652402 (1987-03-01), Brunke et al.
patent: 4666629 (1987-01-01), Wieger et al.
Wawrzencyk et al., "Chem. Abstracts", vol. 96; 122285z (1981).
Derdzinski, "Chemical Abstracts", vol. 96:122286a (1981).
Wawrzenczyk et al., (II)-Juvenoids with Cyclopentene Ring. Synthesis of Isopropyl 3,7-Dimethyl-10-(2,2,3-trimethylcyclopent-3-en-l-yl)-deca-2,8-dienoate and -deca-2,4,8-trienoate, Journal F. Pfraft. Chemie. Band 326, Heft 2, 1984, S. 213-221.

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