1,5-Disubstituted-2-pyrrolidinones, -3-pyrrolin-2-ones, and -4-p

Details 1,5-Disubstituted-2-pyrrolidinones, -3-pyrrolin-2-ones, and -4-p 1,5-Disubstituted-2-pyrrolidinones, -3-pyrrolin-2-ones, and -4-p

1974-08-06

1976-08-17

Ore, Dale R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

26032643, 424244, C07D20728, C07D20730

Patent

active

039753999

ABSTRACT:
Certain 1,5-disubstituted 2-pyrrolidinones, and their ring unsaturated analogs, resemble natural prostaglandins. The compounds are easier to prepare than the prostaglandins since they have at least one fewer center of asymmetry and accordingly fewer isomers are produced. Exemplary is 7-[2-oxo-5-(3-hydroxy-1-oct-1-enyl)-1-pyrrolidinyl]heptanoic acid of the formula: ##SPC1##

REFERENCES:
patent: 3729502 (1973-04-01), Beal et al.
patent: 3767693 (1973-10-01), Samuelsson

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