Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1992-05-04
1994-05-17
Zitomer, Stephanie W.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 911, 935 77, 935 78, C12Q 168, C12P 1934
Patent
active
053127285
ABSTRACT:
A probe for the detection of a nucleic acid target sequence containing a molecular switch comprising three essential elements: a probe sequence of 20-60 nucleotides surrounded by switch sequences of 10-40 nucleotides which are complementary to each other, wherein the state of the switch is useful for selectively generating a detectable signal if the probe is hybridized to a target; also, assays and kits utilizing such probes.
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Buyoli Hilda M. L.
Chu Barbara C.
Guerra Cesar E.
Joyce Gerald F.
Kramer Fred R.
Public Health Research Institute of the City of New York, Inc.
The Salk Institute for Biological Studies
Zitomer Stephanie W.
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