7.alpha.Methoxycephalosporin derivatives

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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544 21, 544 26, C07D50136, A61K 31545

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active

043573312

ABSTRACT:
A 7.alpha.-methoxycephalosporin derivative represented by the formula (I): ##STR1## wherein R.sub.1 represents a heterocyclic ring or an --S-- heterocyclic ring; R.sub.2 represents a hydrogen atom, a carboxy group or a --COOR.sub.5 group wherein R.sub.5 represents a lower alkyl group, a dialkylamino-lower alkyl group or a ##STR2## group wherein R.sub.6 represents a lower alkyl group, a lower acyl group or a lower alkoxycarbonyl group and Y represents a hydrogen atom or a lower alkyl group; R.sub.3 represents a hydrogen atom, a carbamoyl group or a lower acyl group; R.sub.4 represents a hydrogen atom, a lower alkyl group, a dialkylamino-lower alkyl group or a ##STR3## group wherein R.sub.6 and Y are defined as above; A and B, which may be the same or different, each represents a straight chain or branched chain alkylene group having 1 to 5 carbon atoms; and x represents 0 or 1; or a pharmaceutically acceptable salt thereof and a process for producing the same.

REFERENCES:
patent: 4007177 (1977-02-01), Nakao et al.
patent: 4051129 (1977-09-01), Shimizu et al.
patent: 4059578 (1977-11-01), DeMarinis et al.
patent: 4126745 (1978-11-01), Nakao et al.
patent: 4165429 (1979-08-01), Iwanami et al.
patent: 4297488 (1981-10-01), Christensen et al.

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