Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form
Patent
1998-04-17
1999-08-24
Reamer, James H.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Particulate form
514249, A61K 914
Patent
active
059422513
ABSTRACT:
The invention relates to pharmaceutical compositions for the intranasal administration of dihydroergotamine, apomorphine and morphine comprising one these pharmacologically active ingredients in combination with a cyclodextrin and/or a disaccharide and/or a polysaccharide and/or a sugar alcohol.
REFERENCES:
patent: 4659696 (1987-04-01), Hirai et al.
patent: 4727064 (1988-02-01), Pitha
patent: 4834985 (1989-05-01), Elger et al.
patent: 5169840 (1992-12-01), Kiechel et al.
patent: 5506203 (1996-04-01), Buckstran et al.
patent: 5602112 (1997-02-01), Rubinfeld
patent: 5624898 (1997-04-01), Frey
patent: 5629011 (1997-05-01), Illum
Deutsche Apotheker Zeitung, vol. 130, No. 44, Nov. 1, 1990, pp. 2411-2415, Hermens and Merkus, Entitled "Nasale Arneimittel".
Humbert et al., Clin. Pharmacol Ther. 1996; 60:265-275, Human Pharmacokinetics of Dihydroergotamine Administered by Nasal Spray.
Abstract, in press British Journal of Clinical Pharmacology, 1998, Pharmacokinetics of Intranasal Formulations of Dihydroergotamine.
Marttin et al., Journal of Pharmaceutical Sciences, vol. 86, No. 7, Jul. 1997, Nasal Absorption of Dihydroergotamine from Liquid and Powder Formulations.
Martindale, The Extra Pharmacopoeia, 1996, p. 480.
LandOfFree
Pharmaceutical compositions for intranasal administration of dih does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Pharmaceutical compositions for intranasal administration of dih, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pharmaceutical compositions for intranasal administration of dih will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-464464