Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Matrices
Reexamination Certificate
2004-01-28
2009-06-23
Hartley, Michael G (Department: 1618)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Matrices
Reexamination Certificate
active
07550155
ABSTRACT:
The present invention provides aqueous pharmaceutical compositions containing a lipophilic therapeutic agent. In particular, the invention provides aqueous pharmaceutical compositions containing the compound 2,6-diisopropylphenol (propofol). Preferred compositions of the invention contain propofol in the presence of at least one block copolymer (for example, P188 or another poloxamer) and a polyethylene glycol (PEG). Compositions of the invention are preferably sterile or are readily sterilized (e.g., by autoclaving) and are suitable for parenteral administration to any animal, including humans. The compositions are also chemically and physically stable over a wide range of environmental conditions and for extended periods of time.
REFERENCES:
patent: 4056635 (1977-11-01), Glen et al.
patent: 4452817 (1984-06-01), Glen et al.
patent: 4798846 (1989-01-01), Glen et al.
patent: 5296161 (1994-03-01), Wiersema et al.
patent: 5635540 (1997-06-01), Edlich et al.
patent: 5637625 (1997-06-01), Haynes
patent: 5731355 (1998-03-01), Jones et al.
patent: 5962536 (1999-10-01), Komer
patent: 6100302 (2000-08-01), Pejaver et al.
patent: 6140373 (2000-10-01), May et al.
patent: 6140374 (2000-10-01), May et al.
patent: 6150423 (2000-11-01), Carpenter
patent: 6277410 (2001-08-01), Kabanov et al.
patent: 6383471 (2002-05-01), Chen et al.
patent: 6534547 (2003-03-01), Carpenter
patent: 6623765 (2003-09-01), Dennis et al.
patent: 6638537 (2003-10-01), Dennis et al.
patent: 6743436 (2004-06-01), Lee et al.
patent: 7034013 (2006-04-01), Thompson et al.
patent: 7166303 (2007-01-01), Meadows et al.
patent: 2002/0006442 (2002-01-01), Mishra et al.
patent: 2002/0022667 (2002-02-01), Pace et al.
patent: 2002/0107291 (2002-08-01), Tommaso
patent: 2003/0138489 (2003-07-01), Meadows et al.
patent: 2003/0165544 (2003-09-01), Mishra et al.
patent: 2004/0220283 (2004-11-01), Zhang et al.
patent: 2004/0265388 (2004-12-01), Zhang et al.
patent: 2005/0009731 (2005-01-01), Desai et al.
patent: 2005/0027019 (2005-02-01), Zhang et al.
patent: 2 298 789 (1996-09-01), None
patent: 97/10814 (1997-03-01), None
patent: 00/21517 (2000-04-01), None
patent: 00/78301 (2000-12-01), None
patent: 01/64187 (2001-09-01), None
patent: 01/89514 (2001-11-01), None
patent: WO 02/45709 (2002-06-01), None
patent: WO 02/074200 (2002-09-01), None
patent: 03/017977 (2003-03-01), None
patent: 03/030862 (2003-04-01), None
patent: WO 2004/032910 (2004-04-01), None
Adams, Monica L. et al., “Amphiphilic Block Copolymers for Drug Delivery” Journal of Pharm. Sciences, vol. 92, No. 7, Jul. 2003.
Dutta, Sandeep et al., “Formulation-dependent Pharmacokinetics and Pharmacodynamics of Propofol in Rats”, J. Pharm. Pharmacol., 1998, 50:37-42, Aug. 1, 1997.
Ivanova, Rouja et al., “Interaction of Poloxamer Block Copolymers with Cosolvents and Surfactants”, Colloids and Surfaces, Physiochemical and Engineering Aspects 183-185 (2001) p. 41-53.
Momot, Konstantin et al., “NMR Study of the Association of Propofol with Nonionic Surfactants”, School of Molecular and Microbial Biosciences, University of Sydney, Sydney, NS 2006, Australia, and DBL Australia Pty. Ltd., Level 21, 390 St. Kilda Road, Melbourne, Vic 3004, Austalia.
P. Bulet et al., Antimicrobial Peptides in Insects; Structure and Function, Developmental and Comparative Immunology, 23 (1999) 329-344.
F.F. Busta et al., “Chemical Food Preservatives,”Disinfection, Sterilization, and Preservation, pp. 656-694, third edition, Ed SS. Block, 1983, Pub. Lea and Febiger, Philadelphia, USA.
Official Action of Jul. 28, 2005 in U.S. Appl. No. 10/629,308 (with attachments).
Amendment filed Dec. 23, 2005 in response to Official Action of Jul. 28, 2005 in U.S. Appl. No. 10/629,308.
Official Action of Feb. 27, 2006 in U.S. Appl. No. 10/629,308.
Response to Restriction Requirement filed Mar. 27, 2006 in response to Official Action of Feb. 27, 2006 in U.S. Appl. No. 10/629,308.
Official Action of Jun. 29, 2006 in U.S. Appl. No. 10/629,308.
Amendment filed Aug. 18, 2006 in response to Official Action of Jun. 29, 2006 in U.S. Appl. No. 10/629,308.
Advisory Action of Dec. 22, 2006 in U.S. Appl. No. 10/629,308.
Amendment filed Mar. 2, 2007 in response to Official Action of Dec. 22, 2006 in U.S. Appl. No. 10/629,308.
Official Action of Nov. 5, 2007 in U.S. Appl. No. 10/629,308 (with attachments).
Official Action of Jul. 28, 2005 in U.S. Appl. No. 10/677,747 (with attachments).
Amendment filed Nov. 28, 2005 to Official Action of Jul. 28, 2005 in U.S. Appl. No. 10/677,747.
Official Action of Feb. 27, 2006 in U.S. Appl. No. 10/677,747.
Response to Restriction Requirement filed Mar. 27, 2006 in response to Official Action of Feb. 27, 2006 in U.S. Appl. No. 10/677,747.
Official Action of Jun. 30, 2006 in U.S. Appl. No. 10/677,747.
Amendment filed Sep. 1, 2006 in response to Official Action of Jun. 30, 2006 in U.S. Appl. No. 10/677,747.
Official Action of Dec. 22, 2006 in U.S. Appl. No. 10/677,747 (with attachment).
Amendment filed Feb. 6, 2007 in response to Official Action of Dec. 22, 2006 in U.S. Appl. No. 10/677,747.
Offical Action of Jul. 5, 2007 in U.S. Appl. No. 10/677,747 (with attachments).
Amendment filed Oct. 4, 2007 in response to Official Action of Jul. 5, 2007 in U.S. Appl. No. 10/677,747.
Challa, R., et al.; “Cyclodextrins in Drug Delivery: An Updated Review”; AAPS PharmSciTech 2005; Oct. 14, 2005; pp. E329-E357; 6 (2) Article 43; Department of Pharmaceutics, Faculty of Pharmacy, Hamdard University, New Delhi, India.
Lofisson, T., et al.; “Cyclodextrins in drug delivery”; Expert Opinion Drug Delivery; 2005; pp. 335-351; 2 (2); Ashley Publications; University of Iceland, Faculty of Pharmacy, Hagi, Hofivallagata, Iceland.
Amendment filed May 2, 2008 in response to Official Action of Nov. 5, 2007 in U.S. Appl. No. 10/629,308.
Official Action of May 28, 2008 in U.S. Appl. No. 10/677,747.
Official Action of Aug. 19, 2008 in U.S. Appl. No. 10/629,308 (with attachments).
Almarsson Orn
Chen Hongming
Zhang Zhong
Gembeh Shirley V
Hartley Michael G
RatnerPrestia PC
Transform Pharmaceuticals Inc.
LandOfFree
Aqueous pharmaceutical compositions of 2,6-diisopropylphenol... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Aqueous pharmaceutical compositions of 2,6-diisopropylphenol..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Aqueous pharmaceutical compositions of 2,6-diisopropylphenol... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4143276