Radiant energy – Ionic separation or analysis – With sample supply means
Reexamination Certificate
2006-12-21
2009-06-02
Berman, Jack I (Department: 2881)
Radiant energy
Ionic separation or analysis
With sample supply means
C250S281000, C250S282000, C073S864810, C073S864830, C435S288200, C239S695000, C029S890142, C264S164000
Reexamination Certificate
active
07541578
ABSTRACT:
A method of manufacturing a microfluidic device is described. A substrate having at least one device thereon is provided, wherein the device includes at least one channel. Next, a region beside the channel is heated, and then the substrate is pulled to neck the region such that at least one capillary connecting with the channel is formed. The present invention also provides a microfluidic device including a substrate and at least one capillary. In particular, the substrate has at least one device thereon, and the device has at least one channel. The capillary is connected with the channel, wherein the substrate and the capillary are a unity structure such that the interface between the capillary and the channel is dead-volume free.
REFERENCES:
patent: 4600424 (1986-07-01), Flaming
patent: 5145565 (1992-09-01), Kater et al.
patent: 5788166 (1998-08-01), Valaskovic et al.
patent: 5969353 (1999-10-01), Hsieh
patent: 5994696 (1999-11-01), Tai et al.
patent: 6417510 (2002-07-01), Moon et al.
patent: 6459080 (2002-10-01), Yin et al.
patent: 6673253 (2004-01-01), Moon et al.
patent: 6723984 (2004-04-01), McMurtry et al.
patent: 6766817 (2004-07-01), da Silva
patent: 6800202 (2004-10-01), Moon et al.
patent: 6800849 (2004-10-01), Staats
patent: 6818157 (2004-11-01), Kobayashi et al.
patent: 6858842 (2005-02-01), Moon et al.
patent: 7297943 (2007-11-01), Tai et al.
patent: 2004/0036019 (2004-02-01), Goodley et al.
patent: 2004/0067578 (2004-04-01), Axelsson
patent: 2004/0206399 (2004-10-01), Heller et al.
patent: 0030167 (2000-05-01), None
patent: WO 2006/049333 (2006-05-01), None
Article Titled “A Microfabricated Device for Rapid Protein Identification by Microelectrospray Ion Trap Mass Spectrometry” jointly authored by Figeys et al., Analytical Chemistry, vol. 69, No. 16, Aug. 15, 1997.(pp. 3153-3160).
Article Titled “Microfabricated Devices for Capillary Electrophoresis-Electrospray Mass Spectrometry” jointly authored by Zhang et al., Analytical Chemistry, vol. 71, No. 15, Aug. 1, 1999.(pp. 3258-3264).
Article Titled “Microfluidic Devices Connected to Fused-Silica Capillaries with Minimal Dead Volume” jointly authored by Bings et al., Analytical Chemistry, vol. 71, No. 15, Aug. 1, 1999.(pp. 3292-3296).
Article Titled “Development of Multichannel devices with an Array of Electrospray tips for High-Throughput Mass Spectrometry” jointly authored by Liu et al., Analytical Chemistry, vol. 72, No. 14, Jul. 15, 2000.(pp. 3303-3310).
Article Titled “Polymer Microspray with an Integrated Thick-Film Microelectrode” jointly authored by Rohner et al., Analytical Chemistry, vol. 73, No. 22, Nov. 15, 2001.(pp. 5353-5357).
Article Titled “Microfabrication of polydimethylsiloxane electrospray ionization emitters” jointly authored by Kim et al., Journal of Chromatography A, 924(2001) pp. 137-145.
Article Titled “An Electrospray Ionization Source for Integration with Microfluidics” jointly authored by Kameoka et al., Analytical Chemistry, vol. 74, No. 22, Nov. 15, 2002.(pp. 5897-5901).
Article Titled “A Fully Integrated Monolithic Microchip Electrospray Device for Mass Spectrometry” jointly authored by Schultz et al., Analytical Chemistry, vol. 72, No. 17, Sep. 1, 2000.(pp. 4058-4063).
Article Titled “Polymer-Based Electrospray Chips for Mass Spectrometry” jointly authored by Wang et al., the 12th IEEE International Conference on Micro Electro Mechanical Systems (MEMS '99), Orlando, Florida, 1999, pp. 523-528.
Article Titled “A planar on-chip micro-nib interface for NanoESI-MS microfluidic applications” jointly authored by Arscott et al., Journal of Micromechanics and Microengineering, 14(2004) 310-316.
Article Titled “Minimal dead-volume connectors for microfluidics using PDMS casting techniques” jointly authored by Chiou et al., Journal of Micromechanics And Microengineering, 14(2004) 1484-1490.
Article Titled “Microfabricated polymer injector for direct mass spectrometry coupling” jointly authored by Gobry et al., Proteomics 2002, 2, 405-412.
Berman Jack I
Industrial Technology Research Institute
Ippolito Rausch Nicole
Jianq Chyun IP Office
LandOfFree
Microfluidic device and manufacturing method thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Microfluidic device and manufacturing method thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Microfluidic device and manufacturing method thereof will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4139793