Cyclic monophosphates of purine and pyrimidine acyclonucleosides

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...

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514 86, A61K 31675

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active

049668951

ABSTRACT:
The present invention relates to a method for treating mammals having acquired immuno-deficiency syndrome (AIDS) or AIDS-related complex or who are infected with other retroviruses, which comprises the administration of a therapeutically effective amount of a cyclic monophosphate derivative of a purine or pyrimidine acyclonucleoside. Process for the preparation of such compounds and compositions containing such compounds as the active ingredient thereof are also disclosed.

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Bailey et al., J. Chem. Soc., pp. 2767-2775 (1988).
Pandit et al., Synthetic Communications, 2(6)345-351 (1972)

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