9-(3,5-Di-O-acyl-.beta.-D-arabinofuranosyl)adenine compounds and

Details 9-(3,5-Di-O-acyl-.beta.-D-arabinofuranosyl)adenine compounds and 9-(3,5-Di-O-acyl-.beta.-D-arabinofuranosyl)adenine compounds and

1976-05-17

1977-09-13

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

424180, 536 24, C07H 1918

Patent

active

040484327

ABSTRACT:
9-(3,5-Di-O-acyl-.beta.-D-arabinofuranosyl)adenine compounds and their production by reacting in each case a 9-(5-O-tri-substituted-silyl-2,3-di-O-acyl-.beta.-D-arabinofuranosyl)adeni ne compound with a tetraalkylammonium fluoride. The compounds are useful as antiviral agents. The compounds are stable and being lipophilic are adaptable to long-acting and depot injectable pharmaceutical formulation.

REFERENCES:
patent: 3309358 (1967-03-01), Hanze
patent: 3354160 (1967-11-01), Duschinsky et al.
patent: 3457253 (1969-07-01), Wechter
patent: 3651045 (1972-03-01), Haskell et al.

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