Hypolipidemic derivatives of 4,5-dihydro-4-oxofuran-2-carboxylic

Details Hypolipidemic derivatives of 4,5-dihydro-4-oxofuran-2-carboxylic Hypolipidemic derivatives of 4,5-dihydro-4-oxofuran-2-carboxylic

1979-05-10

1981-01-13

Raymond, Richard

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

2603457R, 2603458R, 2603473, 2603475, 424275, 424283, 424285, 546 15, 546283, 549 9, 549 13, 549 60, 549 88, A61K 3134, A61K 31445, C07D21355, C07D30768

Patent

active

042449588

ABSTRACT:
Derivatives of 4,5-dihydro-4-oxofuran-2-carboxylic acid characterized by having two substituents at position 5 and in addition being optionally further substituted at position 3 with a lower alkyl group, as well as esters therefor are disclosed. The foregoing compounds are useful hypolipidemic agents in a mammal. Novel methods for the preparation of these compounds also are disclosed.

REFERENCES:
Rosenkranz et al., Helv. Chim. Acta., vol. 46, (1963), pp. 1259-1285.
Chantegrel, Chemical Abstracts, vol. 87, (1977), 102,101x.

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