Organic compounds -- part of the class 532-570 series – Organic compounds – Chalcogen in the nitrogen containing substituent
Patent
1982-04-30
1984-11-27
Rizzo, Nicholas S.
Organic compounds -- part of the class 532-570 series
Organic compounds
Chalcogen in the nitrogen containing substituent
424246, 544 26, C07D50157, A61K 31545
Patent
active
044852355
ABSTRACT:
Disclosed is a novel cephem compound represented by the formula: ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4 and n are as defined in the specification, which is a useful intermediate for synthesizing various cephalosporin antibiotics having a methoxy group at the 7.alpha.-position thereof. Also disclosed is a process for preparing the same.
REFERENCES:
patent: 4162251 (1979-07-01), Hiraoka et al.
patent: 4229573 (1980-10-01), Shibuya et al.
Diagram--Present Invention & Hiraoka et al., Journal of the American Chemical Society, vol. 99, pp. 505-507, (1977).
J. Org. Chem., vol. 38, No. 5, pp. 943-950, (1973).
Tetrahedron Letters No. 31, pp. 2705-2708, (1975).
Tetrahedron Letters No. 16, pp. 1307-1310, (1976).
Journal of the American Chemical Society, 95:7, pp. 2401-2403, (1973).
Journal of the American Chemical Society, 99:16, pp. 5505-5507, (1977).
Journal of the American Chemical Society, 94:4, pp. 1408-1410, (1972).
Akita Eiichi
Atsumi Kunio
Kai Fumio
Katano Kiyoaki
Nishihata Ken
Meiji Seika Kaisha Ltd.
Rizzo Nicholas S.
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