Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1983-01-26
1987-03-17
Hendricks, Glenna M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514212, 514323, 514414, 548504, 546204, 540602, A61K 3140, C07D20914
Patent
active
046508104
ABSTRACT:
Compounds are disclosed of general formula (I): ##STR1## wherein R.sub.1, R.sub.3, R.sub.4, R.sub.6 and R.sub.7, which may be the same or different, each represents a hydrogen atom or an alkyl group;
REFERENCES:
patent: 3472870 (1969-10-01), Larsen et al.
patent: 4252803 (1981-02-01), Webb
Burger, Alfred, Medicinal Chemistry, vol. II, Wiley-Interscience, New York (1970) pp. 1037-1039, 1224-1226.
Espamer, V., "Gramine Derivatives Antagonistic to 5-Hydroxytryptamine," Science 121 (1955) pp. 369-370.
Shaw, et al., "New Agents Inhibitory to the Pressor Effects of Serotonin," Chem. Abst. 50:14127(h) 19.
Bays David E.
Dowle Michael D.
Webb Colin F.
Glaxo Group Limited
Hendricks Glenna M.
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