Streptomyces sp. MA 7074 (ATCC 55605) used for microbial synthes

Details Streptomyces sp. MA 7074 (ATCC 55605) used for microbial synthes Streptomyces sp. MA 7074 (ATCC 55605) used for microbial synthes

1994-10-25

1997-03-18

Lilling, Herbert J.

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

435118, 435886, C12N 120

Patent

active

056122179

ABSTRACT:
Biotransformation products of a fermentation with culture MA7074 are potent HIV protease inhibitors. These products are useful in the prevention or treatment of infection by HIV and in the treatment of AIDS, either as compounds, pharmaceutically acceptable salts, pharmaceutical composition ingredients, whether or not in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described.

REFERENCES:
patent: 5116756 (1992-05-01), Dumont et al.
patent: 5194378 (1993-03-01), Salituro et al.
patent: 5221625 (1993-06-01), Chen et al.
patent: 5272068 (1993-12-01), Ruby et al.
patent: 5413999 (1995-05-01), Yacca et al.

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