Pyrimidine amides of oleic or linoleic acid, composition contain

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514269, 514274, 544301, 544311, 544316, 544319, 544322, A61K 31505, C07D23942, C07D23960

Patent

active

047229276

ABSTRACT:
Certain disubstituted pyrimidineamides of oleic and linoleic acids are potent inhibitors of the enzyme acyl-CoA:cholesterol acyltransferase and are thus useful agents for inhibiting the intestinal absorption of cholesterol.

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