Optics: measuring and testing – By dispersed light spectroscopy – With sample excitation
Patent
1995-06-06
1999-01-26
Hantis, K.
Optics: measuring and testing
By dispersed light spectroscopy
With sample excitation
356308, G01J 330
Patent
active
058643982
ABSTRACT:
The isotopic composition of a multiatomic isotope-bearing species such as CO.sub.2 in an analyte is measured by maintaining the analyte in a condition such that isotope-bearing species are present in an excited state and directing light at wavelengths corresponding to transition energies of isotope-bearing species with different isotopes. The interaction between the analyte and light at the different wavelengths is monitored, as by monitoring the optogalvanic effect caused by the light of the different wavelengths. The light may be supplied by a laser including the isotope-bearing species. A stable isotope such as .sup.13 C or .sup.18 O can be used as a tracer in a chemical or biological test and detected using the composition-determining method.
REFERENCES:
patent: 3096010 (1963-07-01), Fraser
patent: 4184127 (1980-01-01), Green et al.
patent: 4402606 (1983-09-01), Zalweski et al.
patent: 4585344 (1986-04-01), Webster
patent: 4684805 (1987-08-01), Shu-Ti Lee et al.
patent: 4707133 (1987-11-01), Roberts et al.
patent: 4830010 (1989-05-01), Marshall et al.
patent: 4968887 (1990-11-01), Wong
M. Mochizuki et al., "A Method of Analysis of the Pulmonary Gas Exchange System," Jap. J. Physiol., pp. 435-451, vol. 25, 1975. No Month Available.
Lehmann et al., "Isotope Analysis by Infrared Laser Absorption Spectroscopy," Applied Physics, pp. 153-158, vol. 13, 1977. No Month Available.
N. Kokubun et al., Kagaku to Seibutsu, pp. 384-391, vol. 17, 1979. No Month Available.
G. Krzentowski, et al, "Effect of Physical Training on the Oxidation of an Oral Glucose Load at Rest: A Naturally Labeled .sup.13 C-Glucose Study," Diabete & Metabolisme, pp. 112-115, vol. 9, 1983. No Month Available.
J.P. Bromberg, "Rotations and Vibrations of Molecules," Physical Chemistry, chapter 28, pp. 542-564, Allyn and Bacon, Inc., Boston, Massachusetts, 1980. No Month Available.
M. Lacroix et al. in "Stable Isotopes," Analytical Chemistry Symposia Series, edited by H-L Schmidt et al. Eds., Elsevier: New York, pp. 393-398, vol. 11, 1982. No Month Available.
J. Duchesne et al., in "Stable Isotopes" H.L. Schmidt et al. Eds., Elsevier: New York, 1982, pp. 399-407. No Month Available.
J. Pfaff et al., "An Investigation of the laser optogalvanic effect for atoms and molecules in recombination-limited plasmas," Molecular Physics, pp. 541-566, vol. 52, 1984, No. 3. No Month Available.
S.W. Kim et al., "Optogalvanic Detection of CO.sub.2 Laser Spectra in Electrodeless Radio-Frequency Discharge Plasma," Spectroscopy Letters, pp. 767-779, vol. 18(10), 1985. No Month Available.
H.H. Telle, "Optogalvanic spectroscopy of molecules and complexes," Inst. Phys. Conf. Ser., pp. 1-26, vol. 113, 1990. No Month Available.
E. Lotterer, "The simplified .sup.13 C-urea breath test--One point analysis for detection of Heliobacter pylori infection," pp. 590-594, vol. 29, 1991. No Month Available.
Muenchausen et al., "Optogalvanic Studies with a CO.sub.2 Laser," Optics Communications, pp. 317-321, vol. 45, No. 5, Jan. 1984.**
Nippoldt et al., Optogalvanic Detection of Molecular Absorption, Analytical Chemistry, pp. 1171-1173, vol. 55, No. 7, Jun. 1983, .COPYRGT. 1983 American Chemical Society. **
Tong et al., "Stable-Isotope Ratio Analysis Based on Atomic Hyperfine Structure and Optogalvanic Spectroscopy," Talanta, pp. 659-665, vol. 31, No. 99. ** 1984. No Month Available.
Fraser et al., "New method of respiratory gas analysis: light spectrometer," J. Appl. Physiol., 1001-1007. ** 1985 No Month Available.
Hameau et al., "Infrared Laser Optogalvanic Spectroscopy of Molecules: Doppler Free and Double Resonance Effects," Optics Communications, pp. 423-428, vol. 49, No. 6. ** 1984 No Month Available.
Preston et al., "Rapid Sample Throughput for Biomedical Stable Isotope Tracer Studies," Biomedical and Environmental Mass Spectrometry, pp. 229-235, vol. 16. ** 1988 No Month Available.
C.B. Collins, "Molecular Spectroscopy with Optogalvanic Detection," Journal De Physique, pp. 395-409, 1983. ** No Month Available.
Behrens et al. "High Resolution Optogalvanic Spectroscopy as a Useful Tool in the Determination of Atomic Hyperfine Parameters and Isotopic Shifts," Journal De Physique, pp. 149-168, 1983. ** No Month Available.
P. Camus, "Atomic Spectroscopy with Optogalvanic Detection," Journal de Physique, pp. 87-106, 1983. ** No Month Available.
Lawler et al., "Doppler-Free Intermodulated Optogalvanic Spectroscopy," Physical Review Letters, pp. 1046-1049, vol. 42, No. 16, 1979. ** No Month Available.
Koyama et al., "A Continuous Method for Measuring Acetylene in Expired Gas Using Glow Discharge and its Application to Assessment of Pulmonary Blood Flow," Jap. J. Physiol., pp. 377-388, vol. 24, 1974. ** No Month Available.
"Carbon Dioxide Laser", pp. 2-5 of Laser Processing published by National Science Council of Executive Yuan (Republic of China), May 1987.
"Glow Discharge Mass Spectrometry" (GOMS), pp. 57-58, vol. 73 of Latest Information of Scientific Apparatus published by National Science Council of Executive Yuan (Republic of China), Apr. 1993.
"New Laser Spectroscopic Technique for--Isotope Ratio Analysis" by William G. Tong, Dec. 1984 (Ph.D. thesis submitted to Iowa State University).
Lee--High Resolution Infrared Diode Laser Spectroscopy for Isotope Analysis Measurement of Isotopic Carbon Monoxide, Applied Physics Letters, 48 (10) 10 Mar. 1986, pp. 619-621.
Gagne et al.--Effet Optogalvanique Dans Une Decharge a Cathode Creuse: Mechanisme et Dosage Isotopique de L'aranium, Journal de Physique, C7, No. 1, vol. 44, pp. C7-355 to C7-369 (Nov., 1983) & English translation.
Keller, et al.--Optogalvanic Spectroscopy in a Uranium Hollow Cathode Discharge, Opt. Soc. Am. vol. 69, No. 5, May 1979, pp. 738-742.
Aerodyne Research, Inc.--"A Carbon-13 Isotope Analyzer", NSF Grant No. ISI 88-60778, Abstracts of Phase I Awares, NSF Small Business Innovation Research Program, Nov. 1989.
IEEE Journal of Quantum Electronics, vol. QE-22, No. 2, Feb. 1986, entitled, "Absolute Frequencies of Lasing Transitions in Nine CO.sub.2 Isotopic Species, by L.C. Bradley, K.L. Sooho and C. Freed", Ames Laboratory, Iowa State University, Ames, Iowa 50011, Dec., 1984.
Hantis K.
Rutgers The State University
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