Nucleic acids encoding DNA structure-specific recognition protei

Details Nucleic acids encoding DNA structure-specific recognition protei Nucleic acids encoding DNA structure-specific recognition protei

1991-12-26

1994-10-25

Hill, Jr., Robert J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 231, 435 6, 935 3, 935 9, 935 78, 530350, C17N 512

Patent

active

053590473

ABSTRACT:
DNA structure specific recognition protein of eukaryotic origin and DNA encoding such a factor, as well as probes specific for DNA structure specific recognition protein or DNA encoding it and methods of detecting DNA structure specific recognition protein in eukaryotic cells. In particular, a mammalian cellular factor that selectively recognizes and binds DNA damaged or modified by a drug (the anticancer drug, cis-diamminedichloroplatinum (II) or cisplatin) has been identified.

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