Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1991-12-26
1994-10-25
Hill, Jr., Robert J.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
536 231, 435 6, 935 3, 935 9, 935 78, 530350, C17N 512
Patent
active
053590473
ABSTRACT:
DNA structure specific recognition protein of eukaryotic origin and DNA encoding such a factor, as well as probes specific for DNA structure specific recognition protein or DNA encoding it and methods of detecting DNA structure specific recognition protein in eukaryotic cells. In particular, a mammalian cellular factor that selectively recognizes and binds DNA damaged or modified by a drug (the anticancer drug, cis-diamminedichloroplatinum (II) or cisplatin) has been identified.
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Brown Steven J.
Bruhn Suzanne L.
Donahue Brian A.
Essigmann John M.
Kellett Patti J.
Cermak Shelly Guest
Hill Jr. Robert J.
Massachusetts Institute of Technology
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