Cosmetic and/or pharmaceutical formulations with an improved fee

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Cosmetic – antiperspirant – dentifrice

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Details

514785, 514786, A61K 748, A61K 4710, A61K 4714

Patent

active

056860870

DESCRIPTION:

BRIEF SUMMARY
BACKGROUND OF THE INVENTION

1. Field of the Invention
This invention relates to new cosmetic and/or pharmaceutical formulations which contain as oils Guerbet alcohols based on short-chain fatty alcohol mixtures or esters thereof with selected fatty acids.
2. Discussion of Related Art
The production of cosmetic or pharmaceutical formulations, for example creams, lotions or emollients, involves the use of oil-soluble bases of which the function is to transport polar ingredients, for example active substances or moisture, through the lipid barriers of the skin. Various natural and synthetic oils, for example almond oil or avocado oil or ester oils based on short-chain triglycerides, are suitable for this purpose. The oil components in the formulations in question also perform a skin-care function which is directly related to oiling of the skin. There is a demand among consumers for products which impart a non-tacky, almost instantaneous and relatively long-lasting feeling of smoothness and suppleness to the skin.
The subjective feeling on the skin can be correlated and objectified with the physicochemical parameters of the spreading of the oils on the skin, as illustrated by U. Zeidler in Fette, Seifen, Anstrichmitt. 87, 403 (1985). According to this reference, cosmetic oils can be classified as low-spreading (below 300 mm.sup.2 /10 mins.), medium-spreading (around 300 to 1000 mm.sup.2 /10 mins.) and high-spreading oils (above 1000 mm.sup.2 /10 mins.).
If a high-spreading oil is used as the oil component in a predetermined formulation, the required feeling of smoothness of the skin is achieved very quickly, although the experience does not last long. Conversely, if low-spreading oils are used, the feeling of smoothness is by no means pronounced and remains largely unchanged over a relatively long period so that it is also unsatisfactory. The logical combination of a low-spreading oil with a high-spreading oil surprisingly does not lead to the required additive effect, instead first the strong smoothing effect of the fast-spreading oil component and then, quite independently, the effect of the slow-spreading oil are subjectively perceived. In practice, therefore, it is normally necessary to use complex mixtures of oils adapted exactly to one another which successively develop their respective effects on the lines of a cascade without adversely affecting one another. It is obvious that the development of systems such as these involves considerable outlay on equipment and is therefore in need of improvement from the economic
Accordingly, the problem addressed by the present invention was to provide new cosmetic and/or pharmaceutical formulations which would be free from the disadvantages mentioned above.


DESCRIPTION OF THE INVENTION

The present invention relates to cosmetic and/or pharmaceutical formulations with an improved feeling on the skin which are characterized in that they contain Guerbet alcohols based on fatty alcohol mixtures containing 6 to 12 carbon atoms and/or esters thereof with fatty acids containing 6 to 22 carbon atoms, the total spreading of the oil components according to Zeidler being in the range from about 300 to 1000 mm.sup.2 /10 mins.
It has surprisingly been found that cosmetic or pharmaceutical formulations which contain Guerbet alcohols based on fatty alcohol mixtures with the chain length mentioned and/or esters thereof as oils impart the required instantaneous and relatively long-lasting feeling of smoothness to the skin. If, by contrast, Guerbet alcohols based on the pure fatty alcohols are used instead of these Guerbet alcohols or if the Guerbet alcohols based on the pure fatty alcohols are correspondingly mixed, a significantly poorer feeling of the skin is achieved.
In the Guerbetization of alcohol mixtures, mixed Guerbet alcohols are also inevitably formed. Mixed compounds such as these are neither present in Guerbet alcohols obtained by Guerbetization of the pure fatty alcohols nor are they obtainable by mixing Guerbet alcohols based on pure fatty alcohols. However, the i

REFERENCES:
Seifen-Ole-Fette-Wachse, vol. 117, No. 10, 1991 Augsburg, De, pp 369-371, Ansmann et al. `Cosmetic Water in Oil Emulsions- How to Formulate Elegant Skin Care Products`.
Fette, Seifen, Anstrichmitt. 87, p. 403 (1985).
A. Ansmann, SOFW-Journal, 120, 158 (1994).
Soap Cosm. Chem. Spec. Apr., 52 (1987).
"Kosmetische Farbemittel" of the Farbstoffkomission der Deutschen Forschungsgemeinschaft, published by Verlag Chemie, Weinheim, 1984, pp. 81 to 106.

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