Pyridyl-substituted benzothiophenes

Details Pyridyl-substituted benzothiophenes Pyridyl-substituted benzothiophenes

1985-03-25

1986-09-09

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546270, C07D40906, C07D40912, C07D49504

Patent

active

046110593

ABSTRACT:
The present invention provides novel pyridinyl-benzothiophenes and derivatives thereof which are useful as thromboxane A.sub.2 (TXA.sub.2) synthetase inhibitors and as such represent potent pharmacological agents.

REFERENCES:
patent: 4112224 (1978-09-01), Bundy
patent: 4259338 (1981-03-01), Paioni et al.
D. Harris, et al., Advances in Prostaglandin and Thromboxane Research 6:437 (1980).
T. Miyamoto, et al., Advances in Prostaglandin and Thromboxane Research 6:443 (1980).
H. Tai, et al., Advances in Prostaglandin and Thromboxane Research 6:447 (1980).

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