Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1989-10-25
1991-09-03
Ivy, C. Warren
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514461, 549222, 549295, 549321, 549323, A61K 3134, C07D30728, C07F 928
Patent
active
050455648
ABSTRACT:
New 2-furanone compounds have calcium channel antagonist activity and are useful as anti-inflammatory agents and in treating psoriasis.
REFERENCES:
patent: 2359096 (1944-09-01), Elderfield
patent: 2359208 (1944-09-01), Elderfield
patent: 4447445 (1984-05-01), Jacobs
patent: 4786651 (1988-11-01), Wheeler
patent: 4789749 (1988-12-01), Jacobs et al.
patent: 4855320 (1989-08-01), Chatterjee et al.
Tocanne, et al "Absolute configuration of optically active paraconic acid" CA 69 76581k (1968).
Kazuhiko Tanaka, et al, dianions of 8-Hydroxy Sulfones: New and General Approach to Selective Synthesis of 2(5H)-Furanones, Chemistry Letters, pp. 633-636, 1983.
Steven P. Tanis, et al, Furans in Synthesis 4. Silyl Furans as Butenolide Equivalents, Tetrahedron Letters, vol. 25, No. 40, pp. 4451-4454, 1984.
Bonjouklian, et al., Chemical Abstracts, vol. 106, 156260c, p. 670 (1987).
Reynolds, et al, J. Am. Chem. Soc., 110, pp. 5172-5177 (1988).
Deems, et al, Biochimica et Biophysica Acta, 917 pp. 258-268 (1987).
Scheuer et al., Journal of the American Chemical Society 100:1 p. 307 (Jan. 4, 1978).
Graziano, et al., Chemical Abstracts 107, (1987), 236559t.
Negishi et al., J. Org. Chem 45, pp. 5223-5225, (1980).
Allergan Inc.
Baran Robert J.
Ivy C. Warren
Owens Amelia A.
Szekeres Gabor L.
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