Xanthene and thioxanthene derivatives

Details Xanthene and thioxanthene derivatives Xanthene and thioxanthene derivatives

1979-12-21

1981-06-23

Schwartz, Richard A.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

260335, 42424851, 424250, 424251, 424267, 544 63, 544 96, 544130, 544238, 544316, 544319, 544333, 544364, 546187, 546196, 549 27, C07D40904

Patent

active

042752094

ABSTRACT:
The present invention relates to novel thioxanthene and xanthene derivatives which have useful pharmacodynamic activity, such as neuroleptic activity and antiemetic activity, methods for the preparation of said derivatives, pharmaceutical compositions containing same, and a method for the treatment of psychic disorders by administering a therapeutically active amount of one of said derivatives to a living animal body, including human beings.
The new compounds of the present invention corresponds to the Formula I: ##STR1## wherein X is a halogen atom, an alkyl group with from one to four carbon atoms inclusive, an alkyloxy group with from one to four carbon atoms inclusive, a methylthio group, a methylsulphonyl group, a dimethylsulfamoyl group, a trifluoromethyl group or an acetyl group;

REFERENCES:
patent: 3470188 (1969-09-01), Kaiser et al.
patent: 4031222 (1977-06-01), Remy
patent: 4073912 (1978-02-01), Kaiser et al.
patent: 4086350 (1978-04-01), Zirkle

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