Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2007-10-30
2007-10-30
Seaman, Margaret D. (Department: 1625)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C540S580000
Reexamination Certificate
active
10547407
ABSTRACT:
The present invention relates to the synthesis of intermediates for the preparation of compounds of formula (A): wherein n is 2 or 3 and various salt forms of these compounds. The compounds of formula (A) are useful as ανβ3 receptor antagonists
REFERENCES:
patent: 6410526 (2002-06-01), Duggan et al.
Davies et al., Tetrahedron Letters, 2004, “An efficient one-pot synthesis of annulated pyridines utilising a directed ortho-metallation/transmetallation approach”, vol. 45, pp. 1721-1724.
Reed J.N. et al, “Synthesis of 1,2,3,4-Tetrahydroquinolines and 1,2,3,4-Tetrahydro-1,6-Naphthyridines by a Directed Lithiation Reaction 1”, Tetrahedron Letters, vol. 29, No. 45, pp. 5725-5728, 1988.
Bishop Brian Christopher
Brands Karel Marie Joseph
Cottrell Ian Frank
Cowden Cameron John
Davies Antony John
Beeler Nicole M.
Merck & Co. , Inc.
Merck Sharp & Dohme Ltd.
Muthard David A.
Rahmani Niloofar
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