α-N-acetylgalactosaminidase from Clostridium perfringens

Details α-N-acetylgalactosaminidase from Clostridium perfringens α-N-acetylgalactosaminidase from Clostridium perfringens

2006-07-11

2006-07-11

Rao, Manjunath N. (Department: 1652)

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

C435S004000, C435S006120, C435S069100, C435S183000, C435S200000, C435S252300, C435S320100, C536S023200, C536S023700, C530S350000

Reexamination Certificate

active

07074605

ABSTRACT:
An isolated and purified α-N-acetyl-D-galactosaminidase fromClostridium perfringensand homologs thereof are disclosed. A method for purifying and isolating the α-N-acetylgalactosaminidase fromClostridium perfringensby removing neuramidases is disclosed. A process for using the α-N-acetylgalactosaminidase fromClostridium perfringensin altering type A blood cells to type O blood cells is disclosed. A process for altering cells expressing blood group A epitope by using α-N-acetylgalactosaminidase isolated fromClostridium perfringensin altering the cells expressing blood group A epitope to cells expressing blood group O epitope is disclosed.

REFERENCES:
Levy et al. (J. Biol. Chem., 1980, vol. 235(24):11737-11742).

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