Δ 15 -D-Homosteroids with androgenic action

Details Δ 15 -D-Homosteroids with androgenic action Δ 15 -D-Homosteroids with androgenic action

2008-06-17

2008-06-17

Badio, Barbara P. (Department: 1617)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

C552S502000, C514S841000

Reexamination Certificate

active

07388003

ABSTRACT:
The invention relates to Δ15-D-homosteroids of general formula (I)process for their production and pharmaceutical compositions that contain these compounds.The compounds of general formula I according to the invention have androgenic activity.

REFERENCES:
patent: 4057561 (1977-11-01), Fürst et al.
patent: 1054262 (1967-01-01), None
patent: 1564144 (1980-04-01), None
patent: 1569221 (1980-06-01), None
patent: WO 2004/032897 (2004-04-01), None
Avery et al., “Synthesis and testing of 17aβ-hydroxy-7α-methyl-D-homoestra-4, 16-dien-3-one: a highly potent orally active androgen”, Steroids, 1990, vol. 55, February, pp. 59-64.
Wölfling et al., “Synthesis of novel halogen-containing D-homoestrone and 13α-D-homoestrone derivatives by Lewis acid-induced intramolecular Prins reaction”, Tetrahedron 58 (2002) 6851-6861.
International Search Report for Application No. PCT/EP2004/009468 dated Dec. 17, 2004.

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