Water-soluble biologically active ammonium salts

Details Water-soluble biologically active ammonium salts Water-soluble biologically active ammonium salts

1991-05-24

1993-06-22

Ivy, C. Warren

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

536 2854, 544236, 544311, 546170, C07D40104

Patent

active

052217914

ABSTRACT:
This invention relates to hydrolysis resistant, water-soluble ammonium salt solids which are biologically active and which are described by the formula ##STR1## wherein m has a value of from 1 to 3; n has a value of from 1 to 4 and is equal to the free valences in anion R; p has a value of from 1 to 3; R.sub.1, R.sub.2 and R.sub.3 are each independently selected from the group of hydrogen, and C.sub.1 to C.sub.2 alkyl; R.sub.5 and R.sub.6 are each independently selected from the group of hydrogen, hydroxyalkyl and alkoxyalkyl radicals having from 1 to 10 carbon atoms and R is the anion of a biologically active, water-insoluble anion having at least 1 deprotonized hydrogen and is derived from a biologically active, acidic, organic compound selected from the group of a carboxylic, thiocarbonic, sulfonic, sulfinic, thiosulfonic, thioacid, mono- and di- thiophosphate and phosphorous containing acid, having a pKa* value less than 5.

REFERENCES:
patent: 4931566 (1990-06-01), Suber et al.

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