Water soluble agents effective as immunological adjuvants for st

Details Water soluble agents effective as immunological adjuvants for st Water soluble agents effective as immunological adjuvants for st

1978-05-15

1983-01-25

Phillips, Delbert R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07C10352

Patent

active

043702651

ABSTRACT:
Water soluble agents effective as immunological adjuvants for stimulating in the host the immune response to various antigens, comprising an acyl-muramic acid group, wherein acyl means acetyl or glycolyl, and a short peptide chain linked to said acyl-muramic acid group, the first and second amino acids of said peptide chain being preferentially alanine and glutamic acid respectively.

REFERENCES:
patent: 4082736 (1978-04-01), Jones et al.
patent: 4094971 (1978-06-01), Chedid et al.
Kotani, et al., Biken Journal, vol. 18, 105-111, 1973.
F. Audibert, et al., Cell. Immun., 21, 243-249, (1976).
J. Med. Chem. 9, 1966, 971-973.
USPQ vol. 172, pp. 524 & 529, (1972).

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