Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Patent
1987-01-21
1988-09-06
Schenkman, Leonard
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
514732, 514863, A61K 3117
Patent
active
047693908
ABSTRACT:
A pharmaceutical preparation for topical treatment of skin disorders, particularly psoriasis, comprising active ingredients consisting essentially of combinations of 1,8,9-anthracenetriol, and/or derivatives thereof, and urea. The subject preparation is applied in an essentially water-free excipient. The preparation includes surfactants, which are ordinarily incompatible with the active ingredients. By the use of surfactant-urea combinations, surfactants can be incorporated into a stable, lipophilic pharmaceutical preparation, whereby after use the surfactants are liberated by the action of water, to form a readily washable emulsion system. The inventive preparation is advantageously used in the "short time" method of therapy of psoriasis.
REFERENCES:
patent: 4291062 (1981-09-01), Leigh et al.
patent: 4551480 (1985-11-01), Stiefel et al.
Mueller Josef
Roelz Wolfgang
Rohm GMBH Chemische Fabrik
Schenkman Leonard
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