Vitamin D3 derivative and treating agent for inflammatory...

Details Vitamin D3 derivative and treating agent for inflammatory... Vitamin D3 derivative and treating agent for inflammatory...

2005-11-01

2005-11-01

Qazi, Sabiha (Department: 1616)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

9,10-seco- cyclopentanohydrophenanthrene ring system doai

C514S167000, C514S449000, C514S450000, C514S451000, C514S460000, C514S461000, C549S292000, C549S295000, C549S273000, C549S266000, C549S321000

Reexamination Certificate

active

06960573

ABSTRACT:
Compounds expressed by the following general formula (1),[wherein, R01and R02are each independently a hydrogen atom or a protecting group for a hydroxyl group; Z is one out of the following formulae (1-1), (1-2), (1-3), (1-4) and (1-5)].The compounds can be used as active ingredients of treating agents for inflammatory respiratory diseases, malignant tumors, rheumatoid arthritis, osteoporosis, diabetes mellitus, hypertension, alopecia, acne, psoriasis, dermatitis, hypercalcemia, hypoparathyroidism and metabolic disorder of cartilage.

REFERENCES:
patent: 5354872 (1994-10-01), Conrow
patent: 5583125 (1996-12-01), Steinmeyer et al.
patent: 5604257 (1997-02-01), Tabe et al.
patent: 5719297 (1998-02-01), Tabe et al.
patent: 5986112 (1999-11-01), Tabe et al.
patent: 6177586 (2001-01-01), Tabe et al.
patent: 619305 (1994-10-01), None
patent: 2 260 904 (1993-05-01), None
patent: 7-173133 (1995-07-01), None
patent: 11-49747 (1999-02-01), None
patent: 98/58909 (1998-12-01), None
Ishizuka et al. (DN 107:52924; HCAPLUS, abstract of J. Biol. Chem. (1987), 262 (15), 7165-70).
XP 002226140, Abstract, JP 10/087495, Apr. 7, 1998.
XP 002226141, Abstract, JP 08/092098, Apr. 9, 1996.
Patent Abstracts of Japan, Publication No. 57-149224, Publication date Sep. 14, 1982, abstract.
Patent Abstracts of Japan, Publication No. 56-026820, Publication date Mar. 16, 1981, abstract.
Patent Abstracts of Japan, Publication No. 63-107928, Publication date May 12, 1988, abstract.
Patent Abstracts of Japan, Publication No. 62-026223, Publication date Feb. 4, 1987, abstract.
Patent Abstracts of Japan, Publication No. 05-294834, Publication date Nov. 9, 1993, abstract.
Patent Abstracts of Japan, Publication No. 07-291868, Publication date Nov. 7, 1995, abstract.
The Journal of Clinical Investigation, vol. 64, No. 1, Jul. 1979, pp. 218-225, “Evidence that Increased Circulating 1ω25-Dihydroxyvitamin D is the Probable Cause for Abnormal Calcium Metabolism in Sarcoidosis”, Norman H. Bell et al.
Cell Calcium, vol. 16, 1994, pp. 112-122, “Activation of phosphoinositide metabolism by parathyroid hormone in growth plate chondrocytes”, M. J. Zuscik et al.
Calcified Tissue International, vol. 50, 1992, pp. 61-66, “Differential Effects of Parathyroid Hormone on Chick Growth Plate and Articular Chondrocytes”, Ian D. Crabb et al.
Endocrinology, vol. 118, No. 6, 1986, pp. 2445-2449, “Parathyroid Hormone Stimulates the Proliferation of Cells Derived from Human Bone”, B. R. MacDonald et al.
The Journal of Clinical Investigation, vol. 83, Jan. 1989, pp. 60-65, “Insulin-like Growth Factor I Mediates Selective Anabolic Effects of Parathyroid Hormone in Bone Cultures”, Ernesto Canalis et al.
J. Org. Chem., vol. 48, 1983, pp. 4433-4436, “Total Synthesis of 1ω25(R)-Dihydroxy Vitamin D326,23(S)-Lactone (Calcitriol Lactone), a Natural Metabolite of Vitamin D3”, Peter M. Wovkulich et al.
Abstract, WO94/07853.

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