Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor
Reexamination Certificate
2008-09-16
2008-09-16
Navarro, Mark (Department: 1645)
Chemistry: molecular biology and microbiology
Micro-organism, per se ; compositions thereof; proces of...
Bacteria or actinomycetales; media therefor
C435S320100
Reexamination Certificate
active
10530083
ABSTRACT:
Expression vectors are described that can efficiently produce virion capsid protein, tumor-associated protein of human papillomavirus on a microbial surface. Bacterial strains harboring such surface display vectors, and the use of the bacterial strains or their extracts or purified products as complex vaccines, are also described. The surface display vectors contain one or more than two genes selected from among pgsB, pgsC and pgsA, encoding a poly-χ-glutamic acid synthetase complex (pgsBCA) of aBacillussp. strain, and genes that encode virion capsid proteins, tumor-associated proteins of human papillomavirus, Methodology for preparing the foregoing vectors, vaccines and transformed microorganisms are also described.
REFERENCES:
patent: 2001-017182 (2001-01-01), None
patent: 10-2001-0044019 (2001-06-01), None
patent: 10-2001-0032824 (2004-04-01), None
patent: WO - 99/01557 (1999-01-01), None
patent: WO - 00/75336 (2000-12-01), None
Plotkin et al (Vaccines W.B. Saunders Co. 1988, p. 571).
Charbit, et al.,J. Immunol., 139:1658 (1987).
Agterberg, et al.,Vaccine, 8:85 (1990).
Felici, et al.,J. Mol. Biol., 222:301 (1991).
Fuchs, et al.,Bio/Technology, 9:1369 (1991).
Hedegaard, et al.,Gene, 85:115 (1989).
Jung, et al.,Nat. Biotechnol., 16:576 (1998).
Jung, et al.,Enzyme Microb. Technol., 22(5):348 (1998).
Lee, et al.,Nat. Biotechnol., 18:645 (2000).
Kornacker, et al.,Mol. Microl., 4:1101 (1990).
Pfister, H., et al.,Adv. Cancer Res., 48:113 (1987).
Pisani et al,Int. J. Cancer, 55:891 (1993).
Koutsky, et al.,N. Eng. J. of Med., 347(21):1645 (2002).
Hagensee, et al.,J. Virol., 67:315 (1993).
Schiller, et al.,Seminars in Cancer Biol., 7:373 (1996).
Bubenik, J., et al.,Neoplasma, 49:285 (2002).
Gao, et al.,J. Gen. Virol., 75:157 (1994).
Meneguzzi, et al.,Virology, 181:62 (1991).
Moss, B. et al.,Proc. Natl. Acad. Sci. USA, 93:11341 (1996).
Ressing, et al.,J. Immunol., 154:5934 (1995).
Thavala, et al.,Proc. Natl. Acad. Sci. USA, 92:3358 (1995).
Ashiuchi, Makato, et al., A Poly-gamma-glutamate Synthetic System ofBacillus subtilisIFO 3336: Gene Cloning and Biochemical Analysis of . . . , Biochem. Biophy. Res. Comm., Sep. 16, 1999, pp. 6-12, vol. 263, No. 1.
Lehtinen, M., et al., Efficacy of preventive human papillomavirus vaccination, Int. J. STD. AIDS, Dec. 2001, pp. 771-776, vol. 12, No. 12.
Hong Seong-Pyo
Jung Chang-Min
Kim Chul-Joong
Lee Jong-Soo
Park Sue-nie
Bioleaders Corporation
Hultquist Steven J.
Intellectual Property / Technology Law
Korea Research Institute of Bioscience and Biotechnology
Navarro Mark
LandOfFree
Vector for anti-HPV vaccine and transformed microorganism by... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Vector for anti-HPV vaccine and transformed microorganism by..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Vector for anti-HPV vaccine and transformed microorganism by... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3947551