Vascular endothelial growth factor C (VEGF-C) protein and...

Details Vascular endothelial growth factor C (VEGF-C) protein and... Vascular endothelial growth factor C (VEGF-C) protein and...

2004-03-03

2010-06-01

Shen, Wu-Cheng Winston (Department: 1632)

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

Method of regulating cell metabolism or physiology

C514S04400A

Reexamination Certificate

active

07727761

ABSTRACT:
Provided are purified and isolated VEGF-C polypeptides capable of binding to at least one of KDR receptor tyrosine kinase (VEGFR-2) and Flt4 receptor tyrosine kinase (VEGFR-3); analogs of such peptides that have VEGF-C-like or VEGF-like biological activities or that are VEGF or VEGF-C inhibitors; polynucleotides encoding the polypeptides; vectors and host cells that embody the polynucleotides; pharmaceutical compositions and diagnostic reagents comprising the polypeptides; and methods of making and using the polypeptides.

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