Valine-containing pseudopeptides with antiviral activity

Details Valine-containing pseudopeptides with antiviral activity Valine-containing pseudopeptides with antiviral activity

1994-09-07

1997-05-27

Grumbling, Matthew V.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 19, 514 20, 544353, 544224, 544335, 530331, 546335, 546336, 546175, 546146, 546147, 548568, 549 53, 549407, C07D24104, C07D21106

Patent

active

056332319

ABSTRACT:
The present invention relates to valine-containing, substituted pseudopeptides of the general formula (I) ##STR1## in which the substituents have the meaning given in the description, to processes for their preparation, and to their use as anti-viral agents, in particular against cytomegaloviruses.

REFERENCES:
patent: 5086069 (1992-02-01), Klein et al.
patent: 5492896 (1996-02-01), Habich et al.
Chemical Abstracts, P.E. Reed et al, vol. 114, No. 17, Apr. 29, 1991 Abstract No. 164760W.
Chemical Abstracts, M. Raju et al., vol. 115, No. 9, Sep. 2, 1991 Abstract No. 92899u.
Galpin et al., "Analogs of chymostatin", Chemical Abstracts 100:19,717u, 1984.
Galpin et al., "Synthetic peptides", Chemical Abstracts 101:23,948h, 1984.
Galpin et al., "Synthetic analogs of the proteinase inhibitor: chymostatin," Chemical Abstracts 101:192,438x, 1984.

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